Molecular Formula | C12H10N2O |
Molar Mass | 198.22 |
Density | 1.10 |
Melting Point | 100-104°C(lit.) |
Water Solubility | <0.01 g/100 mL at 21 ºC |
Solubility | Soluble in about 300 parts of water, 70 parts of benzene, soluble in ethanol and acetone, insoluble in ether. After storage, it can become milk color. |
Vapor Density | 6.2 (vs air) |
Appearance | White crystal or powder |
Color | Off-white, may become cream-colored during storage |
Merck | 14,7214 |
BRN | 4008096 |
Storage Condition | Sealed in dry,Room Temperature |
Stability | Stable. Incompatible with iron, other heavy metals, strong oxidizing agents, strong acids. |
Sensitive | Easily absorbing moisture |
MDL | MFCD00149973 |
Use | Used as a redox indicator, a reagent for the determination of titanium and iron |
Risk Codes | R25 - Toxic if swallowed R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | SF8437000 |
TSCA | Yes |
HS Code | 29339990 |
Hazard Class | 6.1 |
Packing Group | III |
Toxicity | LD50 orally in Rabbit: 132 mg/kg |
Reference Show more | 1. NI kongwei, Zhang Meng, Xu Dalun, etc. Antioxidant activity of Maillard reaction products from enzymatic hydrolysates of crab meat [J]. Journal of Food and Biotechnology, 2015, 29 (03):239-245. 2. Li Dandan, Jiang Tingting, Zhang Yan, Luo Zhang. Screening of antioxidant lactic acid bacteria in traditional yak butter at high altitude [J]. Food and machinery, 2020,36(06):50-55. 3. Wu Baosen, Gu Dahai, Wang Guiying, et al. Antioxidant activity and sodium nitrite scavenging activity of crude peptide from Norton fire leg [J]. Meat Research, 2017, 31(008):6-11. 4. Huang Renshu, Hu Xiaomeng, He Huili. Optimization of ultrasonic-assisted extraction of isoflavones from Pueraria lobata by response surface methodology and determination of reducing power [J]. Chinese Pharmaceutical Journal, 2015, 50(001):51-57. 5. Li Tianye, Liu Weihua [1,2], Liang Na, et al. Evaluation of gingerols and their antioxidant activities in ginger and its processed products [J]. Food Industry, 2016(12):180-183. 6. Zhang Yu, Zhang Xiaona, Xue Qiao Li, etc. Antioxidant effect of mistletoe extract in vitro [J]. The Journal of Light Industry, 2016, 31(003):39-48. 7. Qiulin Li. Study on the mechanism and application of iron-carbon micro-electrolysis coupled with biological denitrification [D]. Chengdu University of Technology, 2020. |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
overview | o-phenanthroline (o-phenanthroline) is a commonly used redox indicator. as a simple, low-cost and fast analysis method, o-phenanthroline colorimetry is widely used in the detection and analysis of iron elements. The principle is that phenanthroline and Fe2 in a solution with pH = 3~9 will form a stable orange-red complex, and the color depth of the complex can be used to determine the content of iron ions in the sample to be tested. Although this method has high sensitivity, it is still affected by other components in the sample. When using this method to determine the content of substances, it is necessary to pay attention to the experimental conditions such as the dosage of phenanthroline, pH environment, reaction time and wavelength. |
biological activity | o-Phenanthroline monohydrate (1,10-Phenanthroline monohydrate) is a metal chelating agent that can prevent streptozotocin-induced chromosome aberration. o-Phenanthroline monohydrate forms a red chelate with Fe2 +, with the maximum absorption at 510 nm. |
Target | Value |
use | used as redox indicator, reagent for determination of ferrous titania photometric analysis to determine copper and ultra-fine blood glucose. Organic synthesis. Redox indicator. Ferrous reagent. Biochemical research. Extraction of platinum. Gravimetric determination of palladium. Masking agent. Colorimetric determination of divalent iron, platinum, palladium, etc. When complexed with copper, it has nuclease activity and has been used to study DNA-protein interaction |